Effect of enteral Granulocyte-Colony Stimulating Factor(G-CSF) in very low birth weight infants.
Not Applicable
- Conditions
- Feeding problem of newborn, unspecifiedCondition 1: feeding tolerance in newborns. Condition 2: Reactions due to drugs administered to newborn.Reactions and intoxications due to drugs administered to fetus and newborn
- Registration Number
- IRCT2016051427886N1
- Lead Sponsor
- eonatal Research Center
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 293
Inclusion Criteria
All preterm newborns with birth weight less than 1500 gram
Exclusion criteria : Congenital anomalies of the gastrointestinal tract (such as omphalocele, gastroschisis, tracheoesophageal fistula); Acquired GI disorders such as GI perforation , obstruction and necrotising enterocolitis; Other major anomalies such as congenital cyanotic heart disease, neural tube defect, diaphragmatic hernia and trisomy
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Feeding tolerance. Timepoint: since start of feeding until full feeding. Method of measurement: ml/kg/day.
- Secondary Outcome Measures
Name Time Method Hospital stay duration. Timepoint: since birth day to discharge date. Method of measurement: hospitalized date.;Duration of parenteral nutrition. Timepoint: since birth day to discotinue parenteral nutrition. Method of measurement: parenteral nutrition dates.;Antibiotic use. Timepoint: daily. Method of measurement: antibiotic use dates.;Rate of necrotizing enterocolitis. Timepoint: daily. Method of measurement: times of occurance.;Death. Timepoint: daily. Method of measurement: numbers of occurance.