Study on the benefits of fluid restriction on the recovery from surgery

Completed

• Conditions: Cancer; pper gastrointestinal and colorectal cancer resection; Malignant neoplasm of colon

• Registration Number: ISRCTN39295230
• Lead Sponsor: orfolk and Norwich University Hospitals NHS Foundation Trust (UK)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2008-10-02
• Last Update Posted: 2015-01-13

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 234

Inclusion Criteria

1. All adult patients (both males and females) undergoing elective colorectal or upper gastrointestinal surgery (gastrectomies, oesophagectomies) cancer resection at the Norfolk and Norwich University Hospital NHS Foundation Trust
2. All patients will have epidurals for pain relief

Exclusion Criteria

1. American Society of Anaesthesiologists (ASA) classification 4 - 5
2. Chronic renal failure defined as a creatinine greater than 140 µmol/L
3. Congestive cardiac failure defined as New York Heart Association (NYHA) class III - IV
4. Pregnancy
5. Diabetes mellitus (excluding diet controlled)
6. Planned post-operative ventilation on intensive treatment unit (ITU)
7. Contraindication to epidural
8. Inability to give informed consent

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Grade II complications and above up to 30 days post-surgery.

Secondary Outcome Measures

Name	Time	Method
1. 30 day post-operative mortality<br>2. Length of hospital stay<br>3. Post-operative hypotensive episodes. Duration of follow-up: 5 days post-operatively.