NCT01529996CompletedNot Applicable
Comparison of the Efficacy Between Pulsed Dye Laser (PDL) and the Microsecond 1064-nm Nd:YAG Laser for Treatment of Diffuse Facial Redness: A Pilot, Prospective Randomized Trial.
Conditions
Interventions
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Sponsor
- Northwestern University
- Enrollment
- 16
- Locations
- 1
- Primary Endpoint
- Rating on global improvement scale
Study Overview
Brief Summary
The primary objective of this study is to compare the efficacy of PDL and the 1064-nm Nd:YAG laser in the treatment of facial redness.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Single Group
- Primary Purpose
- Treatment
- Masking
- Single (Outcomes Assessor)
Eligibility Criteria
- Ages
- 18 Years to 65 Years (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- Yes
Inclusion Criteria
- •Healthy patients 18-55 years of age with erythematotelangiectatic rosacea (as verified by the the PI).
- •Subjects who are willing to provide informed consent for participation in the study.
Exclusion Criteria
- •Pregnant or lactating individuals
- •Subjects who are unable to understand the protocol or to give informed consent.
- •Subjects who have a known history of photosensitive conditions (e.g. Systemic lupus, polymorphous light eruption)
- •Subjects who have facial telangiectasia of diameter greater than 2 mm.
- •Subject who have significant (as determined by the PI) acute inflammatory papules, pustules, and vesicle involving the central face.
Arms & Interventions
YAG laser
Experimental
Intervention: Pulse Dye Laser/YAG laser (Procedure)
Pulse Dye Laer
Active Comparator
Intervention: Pulse Dye Laser/YAG laser (Procedure)
Outcomes
Primary Outcomes
Rating on global improvement scale
Time Frame: four months
Non-treating dermatologists will rate each side of the face using a global improvement scale to evaluate the effectiveness of the two treatments.
Spectrophotometer measurement
Time Frame: four months
Spectrophotometer measurement as the percent resolution on each follow up visit compared to baseline visit
Secondary Outcomes
- Recorded discomfort(four months)
- Patient satisfaction(four months)
- Adverse events(four months)
Investigators
Murad Alam
Professor in Dermatology, Otolaryngology - Head and Neck Surgery, and Surgery-Organ Transplantation
Northwestern University
Study Sites (1)
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