Does MiECC Improve Outcome in Diabetic Patients Undergoing Elective Coronary Bypass Grafting?
- Conditions
- Acute Kidney Injury
- Registration Number
- NCT02672514
- Lead Sponsor
- Herzzentrum Coswig
- Brief Summary
The aim of this study was to prospectively evaluate MECC compared with conventional extracorporeal circulation of diabetic patients undergoing elective coronary revascularization procedures. The investigators focused on the effects of extracorporeal circulation especially the renal function between both groups.
- Detailed Description
Cardiopulmonary bypass (CPB) is known having a negative influence referring to systemic inflammatory reaction after cardiac surgery which can cause acute kidney injury (AKI). Miniaturized extracorporeal circulation (MECC) attempts to reduce the adverse effects of conventional extracorporeal circulation bypass. Finally, AKI after CPB is a significant clinical problem that increasingly complicates the course of hospitalization and clinical outcome.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 104
- diabetes mellitus type 2
- isolated elective coronary revascularization
- urgent or emergent Status
- Re-Operation
- preexisting reanimation
- preexisting renal transplantation
- chronic kidney insufficiency (GFR < 30 ml/min)
- renal cell carcinoma
- renal artery Stenosis
- heart valve disease (middle- and high-grade)
- endocarditis
- infections (HIV, Tbc and all types of Hepatitis)
- hepatic cirrhosis
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method Acute Kidney Injury within the first 30 days (plus or minus 3 days) after surgery
- Secondary Outcome Measures
Name Time Method
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.