Effect of Nigella sativa and tamsulosin on urinary stones
Phase 2
Recruiting
- Conditions
- Calculus of kidney and ureter.N20.2Calculus of kidney with calculus of ureter
- Registration Number
- IRCT20081011001323N23
- Lead Sponsor
- Yasouj University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 80
Inclusion Criteria
Age more than18 years old
Suffering from renal or ureteral stone less than 10 millimeter
Having informed consent form
Exclusion Criteria
Uncontrolled coagulopathy
Pregnancy
Azotemia
Allergy to medical or herbal drugs
Severe cardiovascular or pulmonary disease
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Passage of renal and upper ureteral stones with sizes from 4-10 millimeter. Timepoint: Two weeks and one month after start of treatment. Method of measurement: Taking KUB(kidney,ureter and bladder) and ultrasonography and report of patients.;Pain severity score due to passage of stones. Timepoint: During study and two weeks and one month after start of treatment. Method of measurement: With Visual Analogue Scale(VAS).
- Secondary Outcome Measures
Name Time Method
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular mechanisms underlie Nigella sativa's effect on renal stone passage compared to tamsulosin?
How does Nigella sativa compare to alpha-blockers in managing ureteral stone-related pain and spontaneous passage rates?
Are there specific biomarkers that predict response to Nigella sativa in patients with 4-10mm kidney stones?
What are the potential adverse events associated with Nigella sativa in urolithiasis treatment and how do they compare to tamsulosin?
What combination therapies with Nigella sativa show promise in urolithiasis management compared to monotherapy with tamsulosin?