ISRCTN85986368进行中（未招募）Unknown
Imaging of tumour microvasculature using high-resolution contrast-enhanced ultrasound together with markers of proliferation/angiogenesis/vascular mimicry to characterise the response to neoadjuvant chemotherapy in triple-negative breast cancer
适应症
试验速览
- 阶段
- Unknown
- 状态
- 进行中（未招募）
- 入组人数
- 5
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
- 性别
- Female
入选标准
- •1. Provision of written informed consent
- •2. Biologically female aged 18 to 60 years
- •3. Histologically confirmed TNBC with planned NACT
- •4. In the investigator's opinion, adhering to the trial recommendations and governance
排除标准
- •1. Cannot provide consent
- •2. Previous ipsilateral breast cancer with chemotherapy
- •3. Pregnant or breastfeeding
- •4. Locally advanced or inflammatory breast cancer
- •5. Metastatic breast cancer
- •6. Allergy to ultrasound contrast
- •7. TNBC subtype associated with good prognosis (adenoid cystic carcinoma, secretory carcinoma, acinic cell carcinoma, carcinoma with apocrine differentiation, low-grade metaplastic carcinoma and carcinoma arising in micro glandular adenosis)
- •8. Right to left cardiac shunt
- •9. Uncontrolled hypertension
- •10. Severe pulmonary hypertension
- •11. Recent thromboembolism
- •12. Hypercoagulation disorder
- •13. Adult respiratory distress syndrome
研究者
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