NCT02649881已完成不适用
Diagnosis of Macrophage Coronary Plaque by Optical Tomographic Imaging : A Comparative Study With Coronary Artery of the Transplanted or Autopsy Heart
Young-Hak Kim, MD, PhD1 个研究点 分布在 1 个国家目标入组 20 人开始时间: 2015年5月12日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 20
- 试验地点
- 1
- 主要终点
- ROC curve of diagnosis
研究概览
简要总结
This study evaluated optimal macrophage diagnosis algorithm through comparative analysis between coronary artery, OCT image, and IVUS, and improve a diagnosis rate of vulnerable coronary plaque accompanied with macrophage infiltration.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age 18 and above
- •Patients who are to receive heart transplantation
- •Patients or their legal representatives who gave a prior written consent
排除标准
- •Impossible to OCT and IVUS analysis due to severe coronary stenosis
结局指标
主要结局
ROC curve of diagnosis
时间窗: within 48 hours
Receiver Operating Characteristic curve of diagnosis through existing NSD(normalized standard deviation)-based method and developed algorithm in the diagnosis of coronary plaque accompanied with macrophage infiltration
次要结局
- cholesterol crystal(within 48 hours)
- microcalcification(within 48 hours)
- fibrin accumulation(within 48 hours)
- neoatherosclerosis(within 48 hours)
- elastic lamia(within 48 hours)
研究者
Young-Hak Kim, MD, PhD
Division of Cardiology
Asan Medical Center
研究点 (1)
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