Efficacy of Homoeopathy in the Treatment of Nasal Allergy in Comparison with Allopathy

Phase 3

Not yet recruiting

• Conditions: Allergic rhinitis, unspecified,

• Registration Number: CTRI/2023/10/059150
• Lead Sponsor: Central Council for Research in Homoeopathy

Brief Summary

The study is intended to evaluate the efficacy of individualized homoeopathic treatment compared with Allopathy in treating moderate to severe Allergic rhinitis over one year follow-up period. Further, the study also intends to evaluate the role of homoeopathic organopathic remedies like *Allium cepa, Ambrosia artimisiaefolia, Aralia racemosa, Arum triphyllum, Arundo mauritanica, Euphrasia officinalis, Kali iod, Naphthalinum, Pollantinum, Sabadilla, Sanguinaria nigra, Sinapis nigra, Skookum-chuk* and *Sticta pulmonaria* in the management of acute exacerbations of Allergic rhinitis in the homoeopathic arm. For analysis of the data, the intention-to-treat population is considered. The primary outcome parameters, TNSS, and RCAT scores will be analyzed using the Kruskal Wallis H Test. Other appropriate statistical tools will be used to analyze other variables.

Detailed Description

Not available

Study Timeline

• Study Start: 2023-01-11
• Last Update Posted: 2024-01-23

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: All
• Target Recruitment: 144

Inclusion Criteria

• Patients with a history of an allergic cause and one or more of the following symptoms: episodic rhinorrhoea, sneezing, obstruction of the nasal passages with lachrymation, post-nasal discharge, and pruritus of the nasal mucosa, conjunctiva and oropharynx together with the anterior rhinoscopic findings of pinkish grey pale, boggy mucosa covered with a thin glistening mucous and hypertrophied turbinates.
• Presence of moderate to severe symptoms as per ARIA classification and TNSS.
• Voluntary written informed consent.

Exclusion Criteria

Patients who are not adequately symptomatic (Mild cases as per ARIA classification and TNSS) or have rhinoscopic findings not consistent with the diagnosis of AR Patients with serious illnesses (known cases of severe renal or hepatic diseases, malignancy, etc.) Patients under any medication for the symptoms of Allergic rhinitis in the past 15 days Cases with other causes of chronic rhinitis or complications of AR like nasal polyposis, bacterial sinusitis, etc., Patients with significant psychological diseases Pregnancy and lactation Patients not ready to give informed consent.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Changes in RCAT (Rhinitis Control Assessment Test)	At Baseline and every 3 months
Changes in TNSS (Total Nasal Symptom Score)	At Baseline and every 3 months

Secondary Outcome Measures

Name	Time	Method
Improvement in the quality of life of the patient through RQLQ	Changes in rhinoscopy and AEC.

Trial Locations

Locations (3)

Dr DP Rastogi Central Research Institute for Homoeopathy; 🇮🇳 Nagar, UTTAR PRADESH, India

National Homoeopathy Research Institute in Mental Health; 🇮🇳 Kottayam, KERALA, India

Regional Research Institute (Homoeopathy); 🇮🇳 Medchal, TELANGANA, India

Dr DP Rastogi Central Research Institute for Homoeopathy

🇮🇳Nagar, UTTAR PRADESH, India

Dr Harpreet Kaur

Principal investigator

9810863650

Drharpreetmd@gmail.com