Post-Operative Sub-Tenon Kenalog in Glaucoma Filtering Surgery
- Conditions
- Glaucoma
- Registration Number
- NCT00238563
- Lead Sponsor
- Stanford University
- Brief Summary
Determine efficacy of sub tenon kenalog injections for post-operative management of trabeculectomy procedures.
- Detailed Description
Postoperative sub-Tenon Triamcinolone Acetonide in glaucoma filtering surgery
Objectives: Trabeculectomy is a surgical procedure designed to reduce internal eye pressure by draining fluid from within the eye to the sub-conjunctival (superficial eye lining) space. Scar formation from conjunctival and Tenon's capsule fibroblast proliferation represents the most common cause of failure of trabeculectomies. A number of drugs have been use to prevent failure of trabeculectomies from the scarring process including intraoperative mitomycin C (MMC) and preoperative Triamcinalone Acetonide (TA). Over the past several years, intraoperative MMC has become a preferred method of preventing scar formation. This study looks to determine in a prospective, double-blind, randomized method the long-term efficacy and safety of MMC with postoperative TA compared to the standard practice of intraoperative MMC with postoperative prednisolone acetate drops in preventing scar related failures of trabeculectomies.
Recruitment & Eligibility
- Status
- WITHDRAWN
- Sex
- All
- Target Recruitment
- Not specified
Trabeculectomy surgery patient, age 18 or older -
Pregnant, nursing, age less than 18, known allergy to medication being studied
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Primary Outcome Measures
Name Time Method Intraocular pressure
- Secondary Outcome Measures
Name Time Method visual field progression, need for further surgery or medications
Trial Locations
- Locations (2)
Stanford University School of Medicine
🇺🇸Stanford, California, United States
Santa Clara valley Medical Center
🇺🇸San Jose, California, United States