Effects of a high calcium pre-event meal on biomarkers of calcium homeostasis in female cyclists
Not Applicable
Completed
- Conditions
- Osteopenia (prevention)Oestoporosis (prevention)Musculoskeletal - OsteoporosisDiet and Nutrition - Other diet and nutrition disorders
- Registration Number
- ACTRN12614000675628
- Lead Sponsor
- Australian Institute of Sport - Nutrition, Physiology
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Female
- Target Recruitment
- 32
Inclusion Criteria
Aged 17 to 32 y; greater than or equal to 18 mo cycling racing experience; able to commit to a 10 d camp based at the Australian Institute in Canberra.
Exclusion Criteria
Exclusion criteria were vitamin D deficiency (25-OH Vitamin D < 30 ng/mL), thyroid dysfunction (n=1), liver or kidney dysfunction, regular use of medications or supplements known to affect bone or calcium metabolism or thyroid function (e.g., thiazide diuretics, bisphosphonates, oral steroids).
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The primary outcome of this study was the effects of a calcium pre-exercise meal on the exercise induced changes in bone turnover (formation and resoprtion). This was measured as the average serum concentration of Cross Linked C-Telopeptide of Type I Collagen (CTX-I), Cross Linked C-Telopeptide of Type II Collagen (CTX-II), Parathyroid Hormone (PTH), and bone formation (Procollagen I N-Terminal Propeptide (PINP) measured using Enzyme-Linked immunoSorbent Assay (ELISA)[pre-trial (time = 0 min); pre-exercise (t = 115 min); and immediately post-exercise (t = 210 min), 40 min post-exercise (t = 250 min), 100 min post-exercise (t = 310 min) and 190 min post-exercise (t = 400 min)]
- Secondary Outcome Measures
Name Time Method Gut comfort measured using a custom design Likert scale questionnaire. [pre-trial (time = 0 min); pre-exercise (t = 115 min); and immediately post-exercise (t = 210 min)];Cycling time trial performance measured as the average work completed in the final 10 min of the cycling trial. Average work is measured using a Wattbike ergometer (Nottingham, UK) which estimates power using a load cell placed near the chain of the ergometer. [post-exercise (t = 210 min)]