TRANSdiagnostic Research into Emotional Disorders and Cognitive-Behavioral Therapy of the Adaptive Mind

Recruiting

• Conditions: F32; F33; F34; F38; F39; F40; F41; F42; F43; F45

• Registration Number: DRKS00031206
• Lead Sponsor: Justus-Liebig-Universität Gießen

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2023-05-09
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 200

Inclusion Criteria

Patients who are at the beginning of a psychotherapy (probatory phase) and have psychological problems in the domain of ??emotional disorders (anxiety (associated) or depressive disorder; diagnosis from the sections F32 - F39/F4, ICD-10), age = 18 years, indication for outpatient CBT treatment, willingness to participate in the study, minimum therapy duration of 12 sessions or regular end of therapy before 12 therapy sessions

Exclusion Criteria

Exclusion criteria for all participants:
- Presence of certain diagnoses, namely: diagnoses from section F2 (according to ICD-10; e.g. schizophrenia), acute manic/hypomanic episode (diagnosis from the ranges F30 and F31, ICD-10).
- acute suicidal tendencies
- Presence of psychotic symptoms (e.g. in the context of a major depressive episode)
- organic mental disorders and neurological diseases (e.g. dementia, epilepsy, stroke, multiple sclerosis)
- Age < 18 years
- Insufficient knowledge of German
- Noncorrectable significant impairments in hearing and vision

Additional exclusion criteria study part 2:
- Cardiovascular or respiratory disease (e.g., condition following myocardial infarction, hypertension or hypertension requiring treatment, asthma, chronic obstructive pulmonary disease)
- neurodermatitis on the palms of the hands
- current severe hearing loss
- difficulty breathing during simple physical activities (e.g. walking)
- Pregnancy

Additional exclusion criteria study part 3 (MRI):
standard MRI exclusion criteria

Study & Design

• Study Type: observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The primary outcome is defined as the change score in the GSI (Global Severity Index of the Brief Symptom Inventory; Franke, 2000), measured during the routine diagnostics between therapy sessions 20-24.