Induction of Pluripotent Stem Cells From Human Fibroblasts of DM1 Patients
Not Applicable
Completed
- Conditions
- DM1
- Registration Number
- NCT02084407
- Lead Sponsor
- Institut de Myologie, France
- Brief Summary
The objective of the study is the modelisation of human cardiomyocyts from pluripotent stem cells in order to study the cardiac alterations induced by CTG expansions.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 12
Inclusion Criteria
Not provided
Exclusion Criteria
- no pragnant or nursing women
- patient unable to understand informed consent
- patient under juridic protection
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method Measure of DM1 alterations in human cardiomyocytes derived from induced pluripotent stem cells At baseline
- Secondary Outcome Measures
Name Time Method Molecular changes in human DM1 cardiomyocytes expressing pathogenic CUGexp-RNA At baseline
Trial Locations
- Locations (1)
Institute of Myology
🇫🇷Paris, France
Institute of Myology🇫🇷Paris, France