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Clinical Trials/NCT02084407
NCT02084407
Completed
Not Applicable

Induction of Pluripotent Stem Cells From Human Fibroblasts of DM1 Patients

Institut de Myologie, France1 site in 1 country12 target enrollmentNovember 2013
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ConditionsDM1

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
DM1
Sponsor
Institut de Myologie, France
Enrollment
12
Locations
1
Primary Endpoint
Measure of DM1 alterations in human cardiomyocytes derived from induced pluripotent stem cells
Status
Completed
Last Updated
11 years ago
OverviewInvestigatorsEligibility CriteriaOutcomesSitesSimilar Trials

Overview

Brief Summary

The objective of the study is the modelisation of human cardiomyocyts from pluripotent stem cells in order to study the cardiac alterations induced by CTG expansions.

Registry
clinicaltrials.gov
Start Date
November 2013
End Date
August 2014
Last Updated
11 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Sponsor
Institut de Myologie, France
Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Not provided

Exclusion Criteria

  • •no pragnant or nursing women
  • •patient unable to understand informed consent
  • •patient under juridic protection

Outcomes

Primary Outcomes

Measure of DM1 alterations in human cardiomyocytes derived from induced pluripotent stem cells

Time Frame: At baseline

Secondary Outcomes

  • Molecular changes in human DM1 cardiomyocytes expressing pathogenic CUGexp-RNA(At baseline)

Study Sites (1)

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