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Clinical Trials/NCT02580929
NCT02580929
Unknown
Not Applicable

Effectiveness of Radiotherapy Before Surgery in Patients With High-risk Relapse Hepatocellular Carcinoma

Peking Union Medical College1 site in 1 country50 target enrollmentOctober 2014
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ConditionsCarcinoma, Hepatocellular

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Carcinoma, Hepatocellular
Sponsor
Peking Union Medical College
Enrollment
50
Locations
1
Primary Endpoint
mortality
Last Updated
10 years ago
OverviewInvestigatorsEligibility CriteriaOutcomesSitesSimilar Trials

Overview

Brief Summary

This study aims to evaluate the effectiveness of radiotherapy before surgery in high-risk relapse hepatocellular cancer patients.

Registry
clinicaltrials.gov
Start Date
October 2014
End Date
July 2017
Last Updated
10 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Sponsor
Peking Union Medical College
Responsible Party
Principal Investigator
Principal Investigator

WU FAN

Doctor

Peking Union Medical College

Eligibility Criteria

Inclusion Criteria

  • •Clinical diagnosis of HCC
  • •In high risk of recurrence of HCC but still can endure palliative resection
  • •KPS scores are \>90
  • •With Child-Pugh Class A liver funcion, serum bilirubin\< 1.5\*normal maxism; ALT and AST\< 1.5\*normal maxism; normal creatinine and urea nitrogen; WBC\>4×109/L, Hb\>110g/L, PLT\>90X109/L.
  • •Have signed informed consent

Exclusion Criteria

  • •HCC cannot be operated
  • •With Child-Pugh Class B/C
  • •Have other organ cancer, excluding curative non-melanotic skin cancer and carcinoma in situ of cervix
  • •Have other severe disease
  • •With active hepatitis
  • •Have accepted local radiation therapy in other hospitals
  • •KPS scores≤70
  • •Tumor edges cannot be defined
  • •Have severe cirrhosis complication
  • •Intensity modulated radiation therapy cannot reach required dose

Outcomes

Primary Outcomes

mortality

Time Frame: 5 years

Study Sites (1)

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