Continous Assessment of Cerebral Autoregulation With Near-infrared Spectroscopy

• Conditions: Cerebral Blood Flow; Cerebral Perfusion Pressure

• Registration Number: NCT02959008
• Lead Sponsor: Yu Liyun

Brief Summary

Cerebral autoregulation can be explained by a tight coupling between oxygen supply and demand of the brain, and is essential to maintain a constant cerebral blood flow (CBF) in the context of changes in cerebral perfusion pressure. In this study, investigators use Near-infrared spectroscopy (NIRS) to monitor cerebral autoregulation.

Detailed Description

Near-infrared spectroscopy (NIRS) is a noninvasive technology that real-time monitors cerebral tissue oxygenation index (TOI). Investigators use Near-infrared spectroscopy (NIRS) to monitor cerebral autoregulation of hypertensive participants and non-hypertensive participants.

Study Timeline

• Status Verified: 2016-11
• Study First Submitted: 2016-11-05
• Study First Submitted QC: 2016-11-05
• Study First Posted: 2016-11-08
• Last Update Submitted: 2016-11-15
• Last Update Posted: 2016-11-16
• Study Start: 2016-12
• Primary Completion: 2018-12
• Study Completion: 2019-12

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

• health people, or people with hypertension

Exclusion Criteria

• diabetes, anemia, liver disease, kidney disease.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
range of cerebral autoregulation	30min