A Clinical trial on KADUKKAI POO CHOORANAM in the management of RATHA MOOLAM (BLEEDING HAEMORRHOIDS)
Phase 2
- Conditions
- Health Condition 1: K640- First degree hemorrhoids
- Registration Number
- CTRI/2022/02/040253
- Lead Sponsor
- Government Siddha Medical College and Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1.Patients presenting with the signs and symptoms such as rectal bleeding, mucus discharge from rectum,anal pain, anaemia and constipation.
2.Patients who are willing to take proctoscopical examination and provide blood samples for laboratory investigation.
Exclusion Criteria
1.Patients with age below 20 years and above 55 years.
2.Patients presenting with the following conditions such as 2nd,3rd and 4th degree of haemorrhoids, pregnant and lactating women, external haemorrhoids.fissure in ano, fistula in ano, hypertension, rectal polyp, rectal cancer.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method If during treatment and after treatment reduction of the following symptoms <br/ ><br> 1.Anal pain <br/ ><br> 2.Rectal bleeding <br/ ><br> 3.Anaemia <br/ ><br> 4.Constipation <br/ ><br> 5.Pus and mucus discharge from rectum. <br/ ><br> <br/ ><br>Timepoint: 45 days <br/ ><br> <br/ ><br>
- Secondary Outcome Measures
Name Time Method 1.To evaluate the pharmacological activities of trial drug. <br/ ><br>2.Study about the prevalence of RATHA MOOLAM in relation between diet and lifestyle. <br/ ><br>3.To determine antimicrobial activity of trail drug in different solvents. <br/ ><br>4.To find out primary phytochemical analysis in trail drug. <br/ ><br>5.To evaluate proctoscopical changes in internal haemorrhoids. <br/ ><br>6.To evaluate safety profile for acute and subacute toxicity. <br/ ><br>7.To perform bio chemical analysis.Timepoint: 45 days