Development of non-invasive methods for diagnosis of asthma and chronic obstructive pulmonary disease (COPD) and for difference between asthma and COPD.

Not Applicable

• Conditions: Asthma and chronic obstructive pulmonary disease (COPD).

• Registration Number: JPRN-UMIN000003193
• Lead Sponsor: Department of Biomedical Laboratory Sciences, Shinshu University School of Health Sciences.

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2010-03-01
• Study Completion: 2012-10-01
• Last Update Posted: 17 October 2023

Recruitment & Eligibility

• Status: Complete: follow-up complete
• Sex: All
• Target Recruitment: 90

Inclusion Criteria

Not provided

Exclusion Criteria

Healthy subjects who have smoking history or have histories of asthma or chronic respiratory diseases are excluded. Asthyma patients who have smoking history or severe cardiovascular diseases are excluded. COPD patients complicated with asthma or who have histories of asthma or severe cardiovascular diseases are excluded.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Decreases in respiratory impedance and dynamic hyperinflation and increases in exhaled nitric oxide 30 minute after the inhalation of a short-acting bronchodilator.

Secondary Outcome Measures

Name	Time	Method
Analysis of proteins and peptides in exhaled breath condensate obtained before the inhalation of a short-acting bronchodilator.