Investigating Physiological Adaptations to Weight Loss
Not Applicable
Completed
- Conditions
- Obesity
- Registration Number
- NCT00870259
- Lead Sponsor
- University of Melbourne
- Brief Summary
The purpose of this study is to examine the effect of diet-induced weight loss on the levels of circulating nutrients and hormones which are involved in feelings of hunger and satiety.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 50
Inclusion Criteria
- males and post-menopausal females
- aged over 18 years
- BMI 27-40kg/m2
- weight-stable
Exclusion Criteria
- major comorbid medial condition (including diabetes)
- taking medications known to affect weight
- smoking
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Primary Outcome Measures
Name Time Method Difference in fasting and/or post-prandial hormone levels following weight loss and after weight maintenance compared with baseline 2, 6 and 12 months
- Secondary Outcome Measures
Name Time Method Association of psychosocial factors with successful weight maintenance 12 months Correlation of fasting and post-prandial hormone levels with ratings of hunger and satiety 0, 2, 6 and 12 months Difference in fasting and/or post-prandial hormone levels in ketotic compared with non-ketotic state week 8 vs week 10
Trial Locations
- Locations (1)
Heidelberg Repatriation Hospital
🇦🇺Melbourne, Victoria, Australia