NCT00870259已完成不适用
An Investigation of Physiological Adaptations Contributing to Weight Regain After Weight Loss
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 50
- 试验地点
- 2
- 主要终点
- Difference in fasting and/or post-prandial hormone levels following weight loss and after weight maintenance compared with baseline
研究概览
简要总结
The purpose of this study is to examine the effect of diet-induced weight loss on the levels of circulating nutrients and hormones which are involved in feelings of hunger and satiety.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Basic Science
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •males and post-menopausal females
- •aged over 18 years
- •BMI 27-40kg/m2
- •weight-stable
排除标准
- •major comorbid medial condition (including diabetes)
- •taking medications known to affect weight
结局指标
主要结局
Difference in fasting and/or post-prandial hormone levels following weight loss and after weight maintenance compared with baseline
时间窗: 2, 6 and 12 months
次要结局
- Association of psychosocial factors with successful weight maintenance(12 months)
- Correlation of fasting and post-prandial hormone levels with ratings of hunger and satiety(0, 2, 6 and 12 months)
- Difference in fasting and/or post-prandial hormone levels in ketotic compared with non-ketotic state(week 8 vs week 10)
研究者
Priya Sumithran
Clinical research fellow
University of Melbourne
研究点 (2)
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