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Clinical Trials/CTRI/2025/09/094105
CTRI/2025/09/094105Not yet recruitingPhase 2/3

A comparative study Between magnesium sulphate and ketamine as analgesic in adult patients for laparoscopic cholecystectomy in a tertiary care center double blind randomized controlled study

sapthagiri institue of medical sceinces bengaluru1 site in 1 country80 target enrollmentStarted: September 15, 2025Last updated:
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Trial Snapshot

Phase
Phase 2/3
Status
Not yet recruiting
Sponsor
Enrollment
80
Locations
1
Primary Endpoint
to compare the analgesic effects of intravenous magnesium sulphate and inravenous ketamine in adult patients for laparoscopic cholecystectomy by NRS scoring postoperatively
Study OverviewStudy DesignEligibility CriteriaOutcomesInvestigatorsSitesRecords & IdentifiersSimilar Trials

Study Overview

Brief Summary

it is a double blind randomized controlled study , comaparative between magnesium sulphate and ketamine as analgesic in adult patients for laparoscopic cholecystectomy , postoperatively to access pain by NRS scoring for first 24 hours of postoperative

Study Design

Study Type
Interventional
Allocation
Randomized
Masking
Participant and Investigator Blinded

Eligibility Criteria

Ages
18.00 Year(s) to 60.00 Year(s) (—)
Sex
All

Inclusion Criteria

  • •ASA 1 and 2 BMI 18-28 kg/m2 all patients posted for laparoscopic cholecyestectomy.

Exclusion Criteria

  • •on sedatives/hypnoticspreoperatively psychiatric illness/alcohol abuse patient with known history to allergy to study drug pregnant and lactating mothers surgery duration more than 3 hours.

Outcomes

Primary Outcomes

to compare the analgesic effects of intravenous magnesium sulphate and inravenous ketamine in adult patients for laparoscopic cholecystectomy by NRS scoring postoperatively

Time Frame: To access pain by NRS scoring system postoperatively for first 24 hours

Secondary Outcomes

  • to compare the hemodynamic responsesintraoperatively with intravenous magnesium sulphate and inravenous ketamine(intraoperatively hemodynamic response with study drug and surgery procedure less than 3 hours)

Investigators

Sponsor
sapthagiri institue of medical sceinces bengaluru
Sponsor Class
Private medical college
Responsible Party
Principal Investigator
Principal Investigator

Dr prashanth prabhu j

sapthagiri institue of medical sciences bengaluru

Study Sites (1)

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