Relationship between ocular blood flow and structure-function in glaucoma patients.

Not Applicable

Recruiting

• Conditions: Open angle glaucoma

• Registration Number: JPRN-UMIN000039667
• Lead Sponsor: Japanese Glaucoma Society

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2020-06-01
• Last Update Posted: 17 October 2023
• Study Completion: 2025-03-31

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 308

Inclusion Criteria

Not provided

Exclusion Criteria

1. visual acuity is less than 0.5. 2. refractive error is outside of +/- 6 diopter and cylinder is outside of +/- 2 diopter. 3. Axial length is more than 26.5mm. 4. Participants who have corneal opacity or cataract with Grade III of Emery-Little criteria. 5. False positive, falde negative, and fixation loss is more than 30%. 6. Participants who have experienced ocular surgery except for cataract (include multi fourcal IOL). 7. Participants who have experienced refractive surgery. 8. Participants who have experienced retinal, vitreous and choroidal disease, 9. Participants who have experienced cardiovascular condition or diabetes. 10. Systolic blood pressure at rest is more than 150mmHg or diastolic blood pressure at rest is more than 90mmHg. 11. Participants who have medicines related to ocular blood flow such as calcium blocker, alpha-1 blocker, beta-1 blocker, and PDE5 inhibitor agent. 12. Participants who have allergy for pupil dilation drops. 13. Participants who don't response to pupil dilation drops.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To determine the feature of ocular blood flow among healthy subjects, primary open angle glaucoma, normal tension glaucoma patients.

Secondary Outcome Measures

Name	Time	Method
To compare patients backgrounds (age, gender, blood pressure, visual acuity, corneal curve, reflation, axial length, intra-ocular pressure, visual field sensitivity, perfusion density, retinal nerve fiber thickness, ganglion cell layer thickness, BMI, family history, smoking history) among healthy subjects, primary open angle glaucoma, normal tension glaucoma patients.