Preliminay study of urinary syndecan- 1 measurement to investigate association with onset of vascular- endothelial injury in patients with sepsis
Not Applicable
- Conditions
- sepsis
- Registration Number
- JPRN-jRCT1030230068
- Lead Sponsor
- Tazawa Kazumasa
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- 24
Inclusion Criteria
Sepsis and septic shock patients who need crinical care at general intensive care unit ( GICU) in our institution.
Define of sepsis: Infection diagnoted or suspected, with organ dysfunction with acute elevation of SOFA score over two points.
Define of septic shock: Sepsis with high blood lactate acid above 2 mmol/L (18 mg/dL), and need vasocontractive drug in addition to fluid resuscitation to keep mean arterial blood bressure over 65 mmHg.
Exclusion Criteria
Patients who are not gotten concented, not available to insert cathetel into bladder, not available to take urea, emergent and obvious critical life- threatning situation, and have any possiblity to effect this study.
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method