JPRN-jRCT1030230068
Not yet recruiting
未知
A preliminary study to investigate the efficacy of urinary syndecan-1 as a marker of glycocalyx collapsing and subsequential vascular endothelial infringement in patients with sepsis - PIE US-1M VIPS
Tazawa Kazumasa0 sites24 target enrollmentMay 14, 2023
Overview
- Phase
- 未知
- Intervention
- Not specified
- Conditions
- Not specified
- Sponsor
- Tazawa Kazumasa
- Enrollment
- 24
- Status
- Not yet recruiting
- Last Updated
- 2 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Sepsis and septic shock patients who need crinical care at general intensive care unit ( GICU) in our institution.
- •Define of sepsis: Infection diagnoted or suspected, with organ dysfunction with acute elevation of SOFA score over two points.
- •Define of septic shock: Sepsis with high blood lactate acid above 2 mmol/L (18 mg/dL), and need vasocontractive drug in addition to fluid resuscitation to keep mean arterial blood bressure over 65 mmHg.
Exclusion Criteria
- •Patients who are not gotten concented, not available to insert cathetel into bladder, not available to take urea, emergent and obvious critical life\- threatning situation, and have any possiblity to effect this study.
Outcomes
Primary Outcomes
Not specified
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