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Clinical Trials/JPRN-jRCT1030230068
JPRN-jRCT1030230068
Not yet recruiting
未知

A preliminary study to investigate the efficacy of urinary syndecan-1 as a marker of glycocalyx collapsing and subsequential vascular endothelial infringement in patients with sepsis - PIE US-1M VIPS

Tazawa Kazumasa0 sites24 target enrollmentMay 14, 2023

Overview

Phase
未知
Intervention
Not specified
Conditions
Not specified
Sponsor
Tazawa Kazumasa
Enrollment
24
Status
Not yet recruiting
Last Updated
2 years ago

Overview

Brief Summary

No summary available.

Registry
who.int
Start Date
May 14, 2023
End Date
TBD
Last Updated
2 years ago
Study Type
Observational
Sex
All

Investigators

Sponsor
Tazawa Kazumasa

Eligibility Criteria

Inclusion Criteria

  • Sepsis and septic shock patients who need crinical care at general intensive care unit ( GICU) in our institution.
  • Define of sepsis: Infection diagnoted or suspected, with organ dysfunction with acute elevation of SOFA score over two points.
  • Define of septic shock: Sepsis with high blood lactate acid above 2 mmol/L (18 mg/dL), and need vasocontractive drug in addition to fluid resuscitation to keep mean arterial blood bressure over 65 mmHg.

Exclusion Criteria

  • Patients who are not gotten concented, not available to insert cathetel into bladder, not available to take urea, emergent and obvious critical life\- threatning situation, and have any possiblity to effect this study.

Outcomes

Primary Outcomes

Not specified

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