A randomized controlled clinical trial using alpha-tocopherol and ascorbic acid in the treatment of moderate traumatic brain injury
Phase 3
Completed
- Conditions
- Surgery
- Registration Number
- PACTR202112742845790
- Lead Sponsor
- Jerry Philip
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 120
Inclusion Criteria
1.Age 16yrs and above
2.Moderate head injury (GCS: 9-12)
3.Acute phase of trauma at 72hours or less
4.Brain CT scan within 72hours of injury
Exclusion Criteria
1.Patients with space-occupying lesions requiring emergency evacuation
2.Patients with TBI duration greater than 72hrs
3.Patients with a previous history of craniotomy or any significant neurosurgical intervention
4.Patients with significant concomitant extracranial injuries
5.Patients with history of liver disease, renal disease or bleeding diathesis
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method