Predictive Factors and Autonomy Level Change

Not Applicable

Recruiting

• Conditions: Memory Impairment
• Interventions: Other: The Lawton Instrumental Activities of Daily Living score (IADL), and the disability assessment of dementia score (DAD-6

• Registration Number: NCT02302482
• Lead Sponsor: Hospices Civils de Lyon

Brief Summary

The Alzheimer's disease or related disorders (ADRD) are among the most disabling diseases because of their main features such as cognitive impairment, loss of functional autonomy and behavioural disorders. In absence of current curative treatment, the identification of the predictive risk factors of progression of the disease, evaluated through its main symptoms, represents a major stake of public health. The investigators aimed at developing a database, which includes the patient medical records on a prospective basis, in collaboration with the medical and administrative personal and with the University hospital computer science department. The main objective is to study the predictive factors associated with the change of functional autonomy level, measured every 6 months to 12 months by phone, in a Memory Clinic. The study population would consist in about 1000 patients with ADRD. The length of follow-up of each patient will be 3 years.

Detailed Description

Not available

Study Timeline

• Study Start: 2014-11
• Study First Submitted: 2014-11-14
• Study First Submitted QC: 2014-11-24
• Study First Posted: 2014-11-27
• Status Verified: 2021-06
• Last Update Submitted: 2021-06-25
• Last Update Posted: 2021-06-28
• Primary Completion: 2027-11
• Study Completion: 2027-11

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 10860

Inclusion Criteria

• Patients who undergo a medical visit in the Memory Clinic for the 1st time
• Patients living at home or in housing
• Patients with memory impairment, at all stage of the disease

Exclusion Criteria

• Patients in institution
• Patients under legal protection
• Patients with a hearing or visual impairment, which dot not allow to carry out the examination

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
Functional autonomy level collection	The Lawton Instrumental Activities of Daily Living score (IADL), and the disability assessment of dementia score (DAD-6	Collection of the Functional autonomy level every 6 - 12 months by phone

Primary Outcome Measures

Name	Time	Method
Functional autonomy level	3 years	The scores of "Lawton Instrumental Activities of Daily Living" (IADL) and of "Disability Assessment of Dementia" (DAD-6)

Secondary Outcome Measures

Name	Time	Method
Cognitive function level	3 years	Mini Mental Test examination (MMSE)

Trial Locations

Locations (2)

Hospices Civils de Lyon - Hôpital des Charpennes; 🇫🇷 Lyon, France

Hôpital Dugoujon; 🇫🇷 Caluire-et-Cuire, France