New Technologies for Endoscopic Treatment of Bleeding Gastroduodenal Ulcers
- Conditions
- Ulcer Hemorrhage
- Registration Number
- NCT04239118
- Lead Sponsor
- Voronezh N.N. Burdenko State Medical Academy
- Brief Summary
The purpose of the study was to improve treatment results of patients with bleeding gastroduodenal ulcers by endoscopic applications of autoplasma, enriched with platelets and granular sorbent aseptisorb-A.
- Detailed Description
The clinical study was conducted on the basis of the Voronezh city specialized Center for the treatment of patients with gastrointestinal bleeding. The study included 112 patients with ulcerative gastroduodenal bleeding. All patients were divided into two groups by random sampling: the main group (n=57 people) and the comparison group (n=55 people). In the treatment of patients of the main group (57 people), an individual approach was used with the use of granular sorbent aseptisorb-A and autoplasm enriched with platelets, in the complex endoscopic treatment of bleeding-complicated gastroduodenal ulcers (Patent Russian Federation (RF) № 2632771). In the comparison group (55 people), traditional methods of endoscopic hemostasis were used.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 112
- Gastroduodenal ulcers with bleeding
- Bleedings of other etiology
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method the timing of final hemostasis a week the timing of final hemostasis
- Secondary Outcome Measures
Name Time Method the frequency of recurrent bleeding 1 year the frequency of recurrent bleeding
healing of ulcerative defects 1 year sizes of ulcerative defects
mortality rates 1 year mortality rates
Trial Locations
- Locations (1)
Voronezh State Medical University
🇷🇺Voronezh, Russian Federation
Voronezh State Medical University🇷🇺Voronezh, Russian Federation