NCT04256330招募中不适用
Cardiometabolic Health and Inflammatory Resolution (Kardiometabol hälsa Och Inflammatorisk Resolution)
Göteborg University1 个研究点 分布在 1 个国家目标入组 200 人开始时间: 2020年1月23日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 200
- 试验地点
- 1
- 主要终点
- Inflammatory status
研究概览
简要总结
The aim of this study is to determine how inflammatory resolution impacts cardiometabolic health and disease in subjects that are either lean (18.5-24.9 kg/m2), overweight (25.0-29.9 kg/m2) or obese (>30.0 kg/m2).
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Informed signed consent has been obtained from the volunteer.
- •The volunteer has a BMI greater than 18.5 kg/m2
排除标准
- •The study staff contacting a potential participant perceives that the individual has difficulty understanding the information.
- •An MD determines that the individual is on too many medications to participate
- •The individual takes a medication that is approved by the MD, but he/she is not willing or not able to wait with any potential morning medication until after their fasted blood-draw.
- •The individual is younger than 18 years (relevant for the FAINT-1 and FAINT-2 cohorts)
- •The individual states that they have increased bleeding tendency or are using anti-coagulant (blood thinning) medication.
- •The individual has some form of chronic inflammation.
- •The individual regularly uses medication that affects inflammatory resolution (e.g., low-dose aspirin).
- •The individual uses immunosuppressive drugs (eg, methotrexate).
- •The individual regularly consumes fish oils (omega 3).
- •The individual has significant gastrointestinal problems.
- •The individual smokes or uses chewing tobacco.
- •The individual has been drinking alcohol two days before the study visit.
- •The individual has tattoos or body piercings on the forearms and / or the stomach that can affect the examination.
- •The individual does not follow instructions given in the research study.
结局指标
主要结局
Inflammatory status
时间窗: 2027
The inflammatory status, defined as CRP levels and ability to respond to pro-resolving therapeutics, will be studied in all 6 groups
次要结局
未报告次要终点
研究者
研究点 (1)
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