跳至主要内容
临床试验/CTRI/2016/02/006602
CTRI/2016/02/006602已完成不适用

A prospective, observational study to evaluate the usefulness of gradient of end tidal carbon dioxide between two lungs in supine and lateral position, to predict intraoperative hypoxemia during one lung ventilation, in elective thoracic surgeries.

Tata memorial Hospital1 个研究点 分布在 1 个国家目标入组 50 人开始时间: 2015年9月6日最近更新:

试验速览

阶段
不适用
状态
已完成
入组人数
50
试验地点
1
主要终点
The relationship between the values of gradient of EtCO2 between two lungs in supine and lateral position and PaO2/FiO2 ratio, obtained from aterial blood gas sample.

研究概览

简要总结

This is an observational study to find out whether difference in the EtCO2 from two lungs in supine and lateral position, can be used to predict the intraoperative hypoxemia. In lateral position, there is gravitational distribution of blood flow to dependent lung, and blood flow to non-dependent lung is reduced. Hence, EtCO2s from two lungs would vary. during one lung ventilation, blood flow to the non-dependent lung becomes shunt. More the shunt, more the chances of intraoperative hypoxemia. Hence, gradient of EtCO2 between two lungs can predict intraoperative hypoxemia.

研究设计

研究类型
Observational

入排标准

年龄范围
18.00 Year(s) 至 99.00 Year(s)(—)
性别
All

入选标准

  • Adult patient undergoing thoracic surgery in lateral decubitus position requiring one lung ventilation (OLV) delivered by a double lumen tube (DLT) in whom arterial line has been inserted intraoperatively would be incorporated in the study.

排除标准

  • •Age < 18 yrs •Emergency Surgeries •Surgeries using Bronchial blockers •Patient with Tracheostomy •Arterial line not cannulated at the start of surgery.

结局指标

主要结局

The relationship between the values of gradient of EtCO2 between two lungs in supine and lateral position and PaO2/FiO2 ratio, obtained from aterial blood gas sample.

时间窗: intraoperatively when the samples of arterial blood geses are analysed to note PaO2/FiO2 ratios.

次要结局

未报告次要终点

研究者

申办方类型
Research institution and hospital

研究点 (1)

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