An observational study to check whether diffrernce in the carbon dioxide exhaled from two lungs can predict intraoperative fall in blood oxygen levels during elective thoracic surgeries.

Completed

• Conditions: Patients undergoing elective thoracic surgeries requiring one lung ventilation with the use of double lumen tube

• Registration Number: CTRI/2016/02/006602
• Lead Sponsor: Tata memorial Hospital

Brief Summary

This is an observational study to find out whether difference in the EtCO2 from two lungs in supine and lateral position, can be used to predict the intraoperative hypoxemia. In lateral position, there is gravitational distribution of blood flow to dependent lung, and blood flow to non-dependent lung is reduced. Hence, EtCO2s from two lungs would vary. during one lung ventilation, blood flow to the non-dependent lung becomes shunt. More the shunt, more the chances of intraoperative hypoxemia. Hence, gradient of EtCO2 between two lungs can predict intraoperative hypoxemia.

Detailed Description

Not available

Study Timeline

• Study Start: 2015-09-06
• Study Completion: 2017-05-18
• Last Update Posted: 2022-05-19

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

Adult patient undergoing thoracic surgery in lateral decubitus position requiring one lung ventilation (OLV) delivered by a double lumen tube (DLT) in whom arterial line has been inserted intraoperatively would be incorporated in the study.

Exclusion Criteria

•Age < 18 yrs •Emergency Surgeries •Surgeries using Bronchial blockers •Patient with Tracheostomy •Arterial line not cannulated at the start of surgery.

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The relationship between the values of gradient of EtCO2 between two lungs in supine and lateral position and PaO2/FiO2 ratio, obtained from aterial blood gas sample.	intraoperatively when the samples of arterial blood geses are analysed to note PaO2/FiO2 ratios.

Trial Locations

Locations (1)

Tata memorial Hospital, Mumbai; 🇮🇳 Mumbai, MAHARASHTRA, India

Tata memorial Hospital, Mumbai

🇮🇳Mumbai, MAHARASHTRA, India

Dr Swapnil Y Parab

Principal investigator

022-24177053

swapnil.parab@gmail.com