Cardiovascular risk factors and diastolic funtion long term after early onset preeclampsia.

Recruiting

• Conditions: cardiovascular disease; preeclampsia; endothelial dysfunction; diastolic dysfunction; women's healthcardiovasculaire aandoeningen; preeclampsie; endotheeldysfunctie; diastolische dysfunctie; gezondheid voor vrouwen

• Registration Number: NL-OMON26651
• Lead Sponsor: VU University medical center

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 11 June 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: Not specified
• Target Recruitment: 274

Inclusion Criteria

Women with a history of early preeclampsia (<34 weeks gestation) who gave labour in the a UMC between 1998-2005 (cases)

Women with a history of uncomplicated pregnancy who gave labour after 37 weeks of gestation in a UMC between 1998-2005 and matched for age and delivery date (controls)

Exclusion Criteria

Multiple pregnancy, chronic hypertension, diabetes mellitus before pregnancy or gestational diabetes during the index pregnancy, cardiovascular disease before pregnancy, renal disease, coagulation disorders, pregnancy complicated by fetal anomalies. For controls exclusion: no pregnancies complicated by vascular complications.

Study & Design

• Study Type: Observational non invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
cardiovascular risk factors and diastolic funtion

Secondary Outcome Measures

Name	Time	Method
metabolic syndrome, diabetes