SEP-study: The assessment of normal values in Stress Echocardiographic Parameters in patients after successful mitral valve repair for organic mitral valve regurgitation - SEP-study

niversitair Medisch Centrum Utrecht0 个研究点目标入组 25 人开始时间: 待定最近更新: 2024年4月23日

适应症

试验速览

暂无简介。

•- Age >=18 years;
•- Male or female from all ethnicities;
•- At least 6 months post successful, isolated MV repair. Successful MV repair: when
•there is no or grade 1+ residual or recurrent MV regurgitation, MG <10 mmHg and
•MVA >1.5 cm2 after MV surgery and during follow-up. Isolated MV surgery may
•include a coronary artery bypass graft (CABG);
•- No symptoms (asymptomatic). Symptoms are defined as subjective limitations of
•exercise capacity or complaints expressed by the patient and confirmed by the
•treating cardiologist;

•- Pulmonary hypertension >50 mmHg at rest;
•- Atrial fibrillation (AF) at time of study related stress echo testing;
•- Known contraindication or incapability to perform peak exercise or inability to
•perform physical stress testing;
•- LVEF <45%;
•- NYHA class II and more;
•- Other heart valve disease of more than mild severity;
•- Concomitant surgery during MV repair, e.g. MAZE, TVP procedure;
•- Heart valve surgery prior to MV repair;
•- Congenital heart disease;
•- Disabling comorbidity, e.g. chronic obstructive pulmonary disease (COPD);
•- Unable to provide informed consent.

发起方

niversitair Medisch Centrum Utrecht