A randomized, comparative study of the effectiveness of sartans on the morning hypertension and metabolic abnormality in the Japanese obese patients by the central registration system.[FUJIYAMA-Study]
Not Applicable
Completed
- Conditions
- Hypertension
- Registration Number
- JPRN-C000000324
- Lead Sponsor
- Central Committee of FUJIYAMA Study
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up continuing
- Sex
- All
- Target Recruitment
- 300
Inclusion Criteria
Not provided
Exclusion Criteria
1)Significant hypertensive patient with diastolic blood pressure >=120 mmHg 2)Malignant hypertensive patient 3)Patient with a contraindication to the study drugs (hypersensitivity, significant hepatic diseases, pregnant woman) 4)Patient with urinary protein (qualitative) + to ++ 5)Patient with familial hyperlipidemia (hypercholesterolemia, hypertriglyceridemia) 6)Other patients judged as ineligible for the study
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Home blood pressure in the early morning assessed by the PROBE (prospective, randomized, open-endpoint, blinded) method
- Secondary Outcome Measures
Name Time Method Home blood pressure at bedtime M/E ratio** Casual blood pressure Obesity: body fat percentage, weight, height, BMI** Blood potassium* Serum lipid: total cholesterol*, HDL cholesterol*, LDL cholesterol* Triglyceride* Glucose metabolism: blood glucose*, IRI* , HbAlc*, HOMA-IR** Renal function: urinary microalbumin*, creatinine* Adverse effects assessed by the PROBE method * : measured together by the clinical laboratory assessed by the PROBE method