Chest Compression and Cerebral Oxygenation During Cardiopulmonary Resuscitation

Completed

• Conditions: Providing Sufficient Cerebral Oxygenation During CPR

• Registration Number: NCT03062306
• Lead Sponsor: Nevsehir Public Hospital

Brief Summary

In recent years, monitorizations during Cardiopulmonary Resuscitation (CPR) are inadequate to show the sufficiency of cerebral oxygenation. During CPR, insufficient chest compressions have critical importance for neurological results and life quality after the return of spontaneous circulation (ROSC).

Detailed Description

The Near-Infrared Spectroscopy (NIRS), which is used in measuring the cerebral tissue oxygenation is one of the latest technologies that allow the measurement of brain oxygen saturation. With this study, the issue of whether sufficient cerebral oxygenation is provided during CPR applied to patients that have Cardiac Arrest (CA) will be investigated, and the effect of CPR on the patient prognosis after ROSC will be examined. In this study, the aim is to investigate whether sufficient oxygenation is provided in synchronization with chest compressions during CPR; and to test the regional brain tissue saturation with rSO2 measurement, and the prognosis with Full Outline of UnResponsiveness (FOUR) Score in patients with ROSC.

Study Timeline

• Study First Submitted: 2017-02-16
• Study First Submitted QC: 2017-02-20
• Study First Posted: 2017-02-23
• Study Start: 2017-05-31
• Primary Completion: 2017-08-31
• Study Completion: 2018-08-31
• Status Verified: 2019-02
• Last Update Submitted: 2019-02-20
• Last Update Posted: 2019-02-22

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 20

Inclusion Criteria

1. All patients undergoing cardiac arrest in intensive care unit

Exclusion Criteria

1. Head injury and intracranial bleeding
2. Cerebral ischemic vascular event
3. Pulmonary diseases that may affect blood-oxygen levels
4. Below the age of 18

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The levels of regional brain tissue oxygen saturation (rSO2) providing with chest compressions during Cardiopulmonary Resuscitation (CPR)	About six month	The data will be obtained by using the Near Infrared Spectroscopy (NIRS) Device and will be recorded rSO2 measurement during the resuscitation of the Cardiac Arrest (CA) patients

Secondary Outcome Measures

Name	Time	Method
Change from baseline in consciousness on Full Outline of UnResponsiveness (FOUR) Score at one week	For a week after ROSC	The patient's consciousness will be evaluated by FOUR score in patients with ROSC

Trial Locations

Locations (1)

Mehmet Akif YAZAR; 🇹🇷 Nevsehir, Turkey