ISRCTN15119603CompletedUnknown
Investigating the effects of tryptophan modulation on attention and impulsivity in adults with and without Attention Deficit Hyperactivity Disorder: A double blind randomised controlled trial
Conditions
Trial Snapshot
- Phase
- Unknown
- Status
- Completed
- Sponsor
- King's College London
- Enrollment
- 144
Study Overview
Brief Summary
2023 Results article in https://pubmed.ncbi.nlm.nih.gov/38033150/ (added 05/12/2023)
Study Design
- Study Type
- Interventional
Eligibility Criteria
- Sex
- All
Inclusion Criteria
- •All participants:
- •1. Adults aged 18-35 years
- •Healthy control participants (HC):
- •2. No diagnosis of ADHD and score on the Adult ADHD Self-Report Scale below the threshold indicative of ADHD.
- •3. Existing current diagnosis of ADHD and score on the Adult ADHD Self-Report Scale above the threshold indicative of ADHD.
- •4. Either not receiving ADHD medication and have not received any for a period of at least 3 months or receiving medication for ADHD (psychostimulant or non-stimulant) and adhering to this with a rate of at least 70%.
Exclusion Criteria
- •1. Gluten or lactose intolerance, as participants will be asked to ingest a whey protein drink
- •2. Current or past diagnosis of nutritional, psychiatric (excluding ADHD) or neurological illnesses
- •3. Being pregnant/breastfeeding
- •4. Being a smoker (including e-cigarettes)
- •5. Currently taking medication known to affect the serotonergic system such as antidepressants
- •6. Learning disabilities
- •7. Following a restrictive diet (e.g. keto), as this might interfere with the experiment
Investigators
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