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A study on clinical outcomes of lumbar disc herniation surgery and evaluation of disc degeneration by MRI

Not Applicable
Conditions
lumbar disc herniation
Registration Number
JPRN-UMIN000042282
Lead Sponsor
Hokkaido University Hospital
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete: follow-up continuing
Sex
All
Target Recruitment
35
Inclusion Criteria

Not provided

Exclusion Criteria

(1) Previous surgery involving index lumbar level (2) Prior or planned procedure to fuse the lumbar spine (3) The posterior bending angle of the intervertebral disc is recognized in any of the anterior bending, middle, and posterior bending of the lumbar spine X-ray image (4) Greater than grade I spondylolisthesis or retrolisthesis at affected level (5) Cauda equina syndrome (6) Acute local or systemic infection (7) Active malignancy or other similar comorbidities (8) Drug-dependent patients or alcohol dependence patients (9) Patients suffering from mental illness (10) Current fracture, tumour and/or deformity of the lumbar spine (11) Currently breast-feeding, pregnant, pregnancy during the trial period, or cannot do a highly effective contraceptive method (12) Other clinical trials within 4 weeks (13) Presence of any implanted metal or other contraindication to MRI (14) Contraindicated for this study due to other reasons

Study & Design

Study Type
Observational
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
1) VAS 2) FFD 3) SLR test 4) Modified Schober's test 5) JOA score 6) SF-36 7) ODI 8) RDQ 9) JOABPEQ 10) MRI signal change 11) Evaluation surgery 12) Safety
Secondary Outcome Measures
NameTimeMethod
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