Endoscopic Phenotype of the J pouch in Patients with Ulcerative Colitis: A multi-center retrospective study in Japa
Not Applicable
- Conditions
- lcerative Colitis
- Registration Number
- JPRN-UMIN000047795
- Lead Sponsor
- niversity of Tsukuba
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- 2000
Inclusion Criteria
Not provided
Exclusion Criteria
(1) Patients who were preoperatively diagnosed with Crohn's disease or indeterminate colitis (IBD unclassified) (2) Patients who did not perform pouchoscopies after ileostomy takedown
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The frequency of chronic pouchitis and pouch failure
- Secondary Outcome Measures
Name Time Method Acute pouchitis, Endoscopic phenotype in patients with acute or chronic pouchitis, Early endoscopic phenotype in patients with chronic pouchitis, co-relationship between clinical symptoms and endoscopic phenotype, and so on
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular pathways correlate with J pouch endoscopic phenotypes in ulcerative colitis patients post-surgery?
How do J pouch endoscopic features compare to IPAA outcomes in UC patients under standard-of-care management?
Which inflammatory biomarkers (e.g., IL-23, TNF-α) predict J pouch complications in UC patients?
What adverse events (e.g., pouchitis, strictures) are most prevalent in J pouch UC patients and their management strategies?
How do biologic therapies (anti-TNF, anti-IL12/23) affect J pouch mucosal healing in UC patients?