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Effect of Phyllanthus niruri (Bhumi Amla / keelanelli in tamil) on improving liver functions in patients with liver dysfunction caused by alcohol intake

Phase 2
Conditions
Health Condition 1: null- Mild to moderate alcoholic hepatitis
Registration Number
CTRI/2017/05/008712
Lead Sponsor
JIPMER Intramural fund
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
ot Yet Recruiting
Sex
Not specified
Target Recruitment
100
Inclusion Criteria

Alcoholic hepatitis patients aged 18-65 years with present history of alcohol abuse of either gender as confirmed by CAGE questionnaire score >=2

Patients with abnormal liver function tests with AST/ALT ratio >2

Exclusion Criteria

Patients who are terminally ill (encephalopathy, spontaneous bacterial peritonitis, hepatorenal syndrome) with severe alcoholic hepatitis (Maddreys discriminant function >=32)

Patients with viral and drug induced hepatitis

Patients with comorbid conditions like coronary artery disease, peripheral vascular disease etc.

Pregnant women or lactating mothers; Women in reproductive age group not practicing contraceptive measures

Patients who had participated in other trials in the past three months

Patients on herbal medications

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod
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