Spiral computed tomography scanning for the early detection of lung cancer

Not Applicable

Completed

• Conditions: ung cancer; Lung cancer; Cancer

• Registration Number: ISRCTN30604390
• Lead Sponsor: German Cancer Research Centre (Deutsches Krebsforschungszentrum)

Brief Summary

2021 Results article in https://pubmed.ncbi.nlm.nih.gov/32930386/ (added 27/07/2021)

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2007-07-19
• Study Completion: 2012-02-01
• Last Update Posted: 10 August 2021

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 4052

Inclusion Criteria

1. Age 50-69
2. Smoking history of at least 40 pack-years
3. If under the age of 60, current smokers or ceased smoking within the last five years
4. Able to complete a self-administered epidemiology questionnaire providing details on smoking history, family history of lung and other cancers (if any), occupational history and previous illnesses
5. Agree to be randomised to screening with annual low dose spiral CT plus smoking cessation counseling or only smoking cessation counseling
6. Have signed an informed consent form

Exclusion Criteria

1. History of lung cancer or other malignancy (except basal cell carcinoma)
2. History of a disease that would preclude surgical as well as medical treatment of lung cancer
3. Other serious illness that would reduce life expectancy to less than 10 years

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Mortality from lung cancer at 5 and 10 years.

Secondary Outcome Measures

Name	Time	Method
o secondary outcome measures