Evaluation of the effectiveness of Boswellia -based herbal powder mixture in improving of Alzheimer's patients
- Conditions
- Mild to moderate Alzheimer's.Alzheimer's disease
- Registration Number
- IRCT20210701051755N1
- Lead Sponsor
- Tehran University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 64
people over 50 years old
who have been diagnosed with mild to moderate Alzheimer's disease based on a clinical interview with a DSM-V neurologist
Minimum primary education
Major psychiatric disorders such as depression, schizophrenia; psychotic disorders
Other causes of dementia include pure vascular dementia, airway dementia, and frontotemporal dementia.
Treatable causes of dementia such as metabolic disorders
Patients with severe hepatic impairment (Child-Pugh class c), renal (GFR <25 ml / min) and cardiac (EF <15%)
Taking the drug memantine
Taking any medication or herbal supplement with an effect on cognitive function
Reluctance to continue the plan, at any time and for any reason during the study
Serious side effects during treatment
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Score of cognitive disorders in MMSE, MOCA questionnaires. Timepoint: 3 months from the start of the study. Method of measurement: MMSE(Mini–mental state examination), MOCA(montreal cognitive assessment).;Behavioral Disorders Score in NPI Questionnaire. Timepoint: 3 months from the start of the study. Method of measurement: (Neuropsychiatric Inventor)NPI test.
- Secondary Outcome Measures
Name Time Method Investigation of side effects. Timepoint: monthly. Method of measurement: Ask questions of the patient and record information.