Neurofunctional Correlates of Intentional Actions Towards Food Stimuli
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 48
- 试验地点
- 4
- 主要终点
- BOLD (Blood Oxygen Level Dependent) signal
研究概览
简要总结
In this project, the investigators will explore the cognitive neuroscience of intentional action in relation to food behaviour. To unravel how the brain systems involved in intentional control of actions and how these interact with the reward system in different physiological conditions and in relation to lean-weight or obesity, the investigators will manipulate the degree of intentionality of the behaviours under examination and the level of satiety of the participants.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Basic Science
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 85 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Normal weight (normal BMI)
- •No MRI controindications
- •No neurological or cognitive problems
排除标准
- •Underweight or overweight
- •MRI controindications
- •Neurological or cognitive problems
结局指标
主要结局
BOLD (Blood Oxygen Level Dependent) signal
时间窗: This outcome will be measured on the recruitment day
The investigators will measure the changes of the hemodynamic response (BOLD signal) recorded in the whole brain during the execution of the different experimental tasks (e.g. intentionally guided actions towards stimuli of high or low calories food vs externally guided actions towards stimuli of high or low calories food), in the two groups (fasted and satiated subjects).
次要结局
未报告次要终点