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Clinical Trials/NCT04662606
NCT04662606
Unknown
N/A

Neurofunctional Correlates of Intentional Actions Towards Food Stimuli

I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio2 sites in 1 country48 target enrollmentSeptember 12, 2020

Overview

Phase
N/A
Intervention
Not specified
Conditions
Food Preferences
Sponsor
I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio
Enrollment
48
Locations
2
Primary Endpoint
BOLD (Blood Oxygen Level Dependent) signal
Last Updated
5 years ago

Overview

Brief Summary

In this project, the investigators will explore the cognitive neuroscience of intentional action in relation to food behaviour. To unravel how the brain systems involved in intentional control of actions and how these interact with the reward system in different physiological conditions and in relation to lean-weight or obesity, the investigators will manipulate the degree of intentionality of the behaviours under examination and the level of satiety of the participants.

Registry
clinicaltrials.gov
Start Date
September 12, 2020
End Date
December 1, 2022
Last Updated
5 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Sponsor
I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio
Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Normal weight (normal BMI)
  • No MRI controindications
  • No neurological or cognitive problems

Exclusion Criteria

  • Underweight or overweight
  • MRI controindications
  • Neurological or cognitive problems

Outcomes

Primary Outcomes

BOLD (Blood Oxygen Level Dependent) signal

Time Frame: This outcome will be measured on the recruitment day

The investigators will measure the changes of the hemodynamic response (BOLD signal) recorded in the whole brain during the execution of the different experimental tasks (e.g. intentionally guided actions towards stimuli of high or low calories food vs externally guided actions towards stimuli of high or low calories food), in the two groups (fasted and satiated subjects).

Study Sites (2)

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