The Establishment of Large-sample Database of "Multiple-MRI/Gene/Cognition"

• Conditions: Healthy

• Registration Number: NCT02144467
• Lead Sponsor: Hangzhou Normal University

Brief Summary

Aim to establish a large-sample database of "Multiple-MRI/Gene/Cognition" for healthy Chinese (sample number, 5000; age, 6-70 years). This is a fundamental but very necessary work for future researches such as development, aging, relation of gene and behavior, relation of gene and neuroimaging, relation of behavior and neuroimaging. Importantly, this work will provide a norm for researches on psychological or neurological patients. This large-sample will be shared with world-wide researchers.

Detailed Description

A part of data have been used in a publication which is preparing to submit.

Study Timeline

• Study Start: 2014-05-08
• Study First Submitted: 2014-05-14
• Study First Submitted QC: 2014-05-19
• Study First Posted: 2014-05-22
• Status Verified: 2022-08
• Primary Completion: 2022-08-02
• Study Completion: 2022-08-02
• Last Update Submitted: 2022-08-02
• Last Update Posted: 2022-08-03

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 5000

Inclusion Criteria

• Healthy Chinese
• Age: 6-70 years old
• Right handed
• No smoking or alcoholic addiction

Exclusion Criteria

• Psychological or neurological patients
• Hypertension or cardiopathy patients
• Pregnant woman
• Take medicine or drink tea/coffee before scanning-

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The distribution of the amplitude of blood oxygenation level dependent(BOLD) signal in healthy subjects	up to 15 months	The amplitude of BOLD-functional magnetic resonance imaging(fMRI) signal is a common measure to estimate the brain activity during resting-state. We try to establish its distribution on healthy subjects, which could be a control to examine abnormal brain function in patients.

Trial Locations

Locations (1)

Hangzhou Normal University,Center for Cognition and Brain Disorder; 🇨🇳 Hangzhou, Zhejiang, China