The Establishment of Large-sample Database of "Multiple-MRI/Gene/Cognition"
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 5,000
- 试验地点
- 1
- 主要终点
- The distribution of the amplitude of blood oxygenation level dependent(BOLD) signal in healthy subjects
研究概览
简要总结
Aim to establish a large-sample database of "Multiple-MRI/Gene/Cognition" for healthy Chinese (sample number, 5000; age, 6-70 years). This is a fundamental but very necessary work for future researches such as development, aging, relation of gene and behavior, relation of gene and neuroimaging, relation of behavior and neuroimaging. Importantly, this work will provide a norm for researches on psychological or neurological patients. This large-sample will be shared with world-wide researchers.
详细描述
A part of data have been used in a publication which is preparing to submit.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 6 Years 至 70 Years（Child, Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Healthy Chinese
- •Age: 6-70 years old
- •Right handed
- •No smoking or alcoholic addiction
排除标准
- •Psychological or neurological patients
- •Hypertension or cardiopathy patients
- •Pregnant woman
- •Take medicine or drink tea/coffee before scanning-
结局指标
主要结局
The distribution of the amplitude of blood oxygenation level dependent(BOLD) signal in healthy subjects
时间窗: up to 15 months
The amplitude of BOLD-functional magnetic resonance imaging(fMRI) signal is a common measure to estimate the brain activity during resting-state. We try to establish its distribution on healthy subjects, which could be a control to examine abnormal brain function in patients.
次要结局
未报告次要终点
研究者
Yu-Feng ZANG
deputy director
Hangzhou Normal University