Advanced MRI in Renal Tumors.
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 39
- 试验地点
- 1
- 主要终点
- Discriminating malignant from benign renal lesions using Apparent Diffusion Coefficient (ADC, a metric obtained by diffusion weighted MRI) value distribution analysis.
研究概览
简要总结
Diagnostic imaging for renal masses of unknown nature using conventional imaging modalities such as 3 phase contrast-enhanced computed tomography (CT) is not always conclusive. After (partial) nephrectomy, 10-20 % of the resected tumors show benign histology which could not be identified on diagnostic imaging. With improved imaging techniques available, leading to improvements in characterisation of renal tumors, the number of unnecessary resections may be reduced. The objective of this study is to assess the ability to discriminate oncocytoma from RCC based on the ADC distribution parameters with addition of, tumor volume, and patient demographic characteristics.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Radiologic diagnosis of renal tumor based on previous ultrasonography, CT or MRI examinations.
- •Signed Institutional Review Board (IRB) approved informed consent form.
- •Being at least 18 years of age.
- •Histopathologically confirmed renal tumor diagnosis.
排除标准
- •Relative contra indications for MRI (metal device/foreign bodies, claustrophobia);
- •Active renal or perirenal infection;
- •Minor and/or incapacitated adult.
结局指标
主要结局
Discriminating malignant from benign renal lesions using Apparent Diffusion Coefficient (ADC, a metric obtained by diffusion weighted MRI) value distribution analysis.
时间窗: 45 months
次要结局
- Additional value of tumor volume and patient characteristics to discriminate malignant from benign renal lesions.(45 months)