Feasibility and Safety of Intraoperative Normothermic Intraperitoneal Chemotherapy (NIPEC) following optimal cytoreduction in women with high grade serous epithelial ovarian cancer undergoing interval cytoreductive surgery

Conducting this study is essential to determine whether intraoperative NIPEC can provide a safe and practical intraperitoneal therapy alternative, complement systemic treatment, and potentially improve oncologic outcomes without imposing additional surgical morbidity. Establishing its safety and feasibility is the critical first step before larger trials can evaluate its long-term survival impact, making this investigation both timely and clinically relevant. In the Indian scenario, most patients belong to low socioeconomic class not affordable for HIPEC. In low cost we can provide almost equal results with low morbidity.