Ultrasonography in Norwegian Emergency Department Patients With Suspected Covid-19 Infection

Terminated

• Conditions: COVID-19; Pulmonary Infection; Pneumonia, Viral
• Interventions: Diagnostic Test: Lung ultrasound

• Registration Number: NCT04422691
• Lead Sponsor: St. Olavs Hospital

Brief Summary

In light of the ongoing COVID-19 epidemic in Norway, it is paramount to develop and utilize clinical tools for assessing and risk stratifying patients with suspected coronary infection in the emergency departments. Diagnostic use of ultrasound in viral pneumonias, including COVID-19 has proved to be very useful. The use of ultrasound will assist in quick detection of lung pathology compatible with increasing severity of the COVID-19 disease. At the same time, the use of ultrasound diagnostics in the emergency department could improve logistics and reduce potential exposure of the corona virus to other health personnel.

The purpose of the study is to assess whether ultrasound findings correlates with physical examination, labs, and other imaging diagnostics in patients with suspected or diagnosed COVID-19 disease, as well as assessing whether ultrasound diagnostics can assist in risk stratification. The project is conducted as a prospective multicenter study where ultrasound diagnostics will be performed on patients with suspected coronary infection in the emergency departments. Data collection takes place as part of the daily clinical evaluation of acute patients in the emergency departments. The project is planned to be completed towards the end of 2025.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2020-06-05
• Study First Submitted QC: 2020-06-06
• Study First Posted: 2020-06-09
• Study Start: 2020-07-01
• Status Verified: 2021-06
• Primary Completion: 2021-06-15
• Study Completion: 2021-06-15
• Last Update Submitted: 2021-06-16
• Last Update Posted: 2021-06-22

Recruitment & Eligibility

• Status: TERMINATED
• Sex: All
• Target Recruitment: 5

Inclusion Criteria

• All emergency department patients with suspected or diagnosed COVID-19.

Exclusion Criteria

• Negative screening for COVID-19
• recent negative COVID-19 test
• no indication for isolation in the Emergency Department

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Covid-19 suspected	Lung ultrasound	Emergency department patients with suspected or diagnosed COVID-19 disease. All patients will be screened at triage and put into isolation if suspected disease. Ultrasound of the patients lungs will be performed after patient consent and findings will be recorded and categorized (Soldati et al., 2020). The use of ultrasound and registration of data will not affect the regular patient evaluation, treatment or logistics.

Primary Outcome Measures

Name	Time	Method
Level-of-care	up to 7 days	In-hospital treatment level, e.g. discharge from ED, observational unit, ward, ICU.
Mortality	up to 30 days	30-day mortality

Secondary Outcome Measures

Name	Time	Method
Oxygen usage in the emergency department	Within 24 hours
Emergency department length of stay	Within 24 hours	in hours
In-hospital length of stay	Up to 30 days	in days
Antibiotics usage	Within 24 hours

Trial Locations

Locations (9)

Sørlandet sykehus, Kristiansand; 🇳🇴 Kristiansand, Norway

Ullevål University Hospital; 🇳🇴 Oslo, Norway

Sykehuset Telemark HF; 🇳🇴 Skien, Norway

St Olavs Hospital; 🇳🇴 Trondheim, Norway

Nordland Hospital; 🇳🇴 Bodø, Norway

Akershus University Hospital; 🇳🇴 Oslo, Norway

Stavanger Universitetssjukehus; 🇳🇴 Stavanger, Norway

Drammen sykehus; 🇳🇴 Drammen, Norway

Haukeland universitetssykehus; 🇳🇴 Bergen, Norway