NCT00048022已完成2 期
Inhaled Corticosteroid Replacement Study - Efficacy and Safety of Ro 27-2441 (Test Drug) in Moderate Persistent Asthma
适应症
相关药物
试验速览
- 阶段
- 2 期
- 状态
- 已完成
- 试验地点
- 60
研究概览
简要总结
The primary objective of the study is to evaluate the anti-inflammatory action and safety of Ro 27-2441 (study drug) in asthmatic patients currently taking inhaled corticosteroids. The research is being conducted at up to 40 clinical research sites in the US. Study participants will have a number of visits to a research site over a 4-month period.
研究设计
- 研究类型
- Interventional
- 主要目的
- Treatment
入排标准
- 年龄范围
- 18 Years 至 70 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Persistent asthma for more than 1 year
- •Currently receiving treatment with a stable dose of inhaled corticosteroids for more than 3 months
- •In good health as demonstrated by medical history and physical exam
- •Negative urine pregnancy test
- •Commitment to use two forms of effective contraception simultaneously throughout the study duration and for 1 month after discontinuing therapy
排除标准
- •Hospitalization for treatment of asthma and/or treatment with oral/injectable corticosteroids within 3 months before the start of the study
- •Undergoing allergy shots unless on a stable maintenance dose for 3 months before the start of the study
- •History of chronic pulmonary diseases other than asthma
- •Treatment of conditions other than asthma with oral corticosteroids within 1 month of the start of the study
- •Current tobacco usage
- •Smoking history of greater than 10 pack-year history of cigarette smoking (number of packs smoked per day times the number of years smoked)
- •History or evidence of drug or alcohol abuse
- •Diagnosis or evidence of an infectious illness within one month of Visit 1
- •Clinically significant diseases as assessed by the study doctor
- •Participation in another clinical study with an experimental drug within one month of start of the study
研究者
研究点 (60)
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