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DOSE FINDING PROSPECTIVE ANALYSIS AFTER HEART SURGERY for Sucrosomial Iron

Phase 4
Not yet recruiting
Conditions
Anemia
Interventions
Registration Number
NCT07038330
Lead Sponsor
Cardiochirurgia E.H.
Brief Summary

Randomization to different doses of Sucrosomial Iron for one moth after discharge to rehab after heart surgery to assess if more iron grants a faster recovery or not

Detailed Description

Evaluation of the efficacy of short-term sucrosomial iron treatment in patients undergoing cardiac surgery and subsequently transferred to rehabilitation, measured in terms of increase in hemoglobin values and restoration of martial blood parameters, administering doses of 30mg, 60mg and 120mg respectively, after randomization of patients.

Numerical congruity analysis, power sampling, biometric characteristics of internal compatibility between cohorts and outcome analysis with comparison for continuous homoscedastic case-control variables

Drafting of formal statistical analysis, drafting of information synopsis, writing, validation, forwarding to scientific journal and correction until obtaining, where possible, publications of the manuscript relating to the research.

Recruitment & Eligibility

Status
NOT_YET_RECRUITING
Sex
All
Target Recruitment
150
Inclusion Criteria

Hb<11; Having had Heart Surgery, Being Discharged to Rehab

Exclusion Criteria
  • Hb>11.1, hematological primary disesases

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
30mgSucrosomial Iron1 cp (30mg) per day of Sucrosomial Iron
60mgSucrosomial Iron2 cp (60mg) per day of Sucrosomial Iron
120mgSucrosomial Iron4 cp (120mg) per day of Sucrosomial Iron
Primary Outcome Measures
NameTimeMethod
Hemoglobin30 days

Hemoglobin level at 30 day of treatment

Secondary Outcome Measures
NameTimeMethod
Martial Metabolism30 days

Ferritin, Transferrin, Iron Saturation

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