Efficacy of Exclusive Enteral Nutrition in Adult Active Crohn's Disease

Completed

• Conditions: Efficacy of Exclusive Enteral Nutrition in Adult Active Crohn's Disease With Complications or Failure of Medical Treatment

• Registration Number: NCT02887287
• Lead Sponsor: Sun Yat-sen University

Brief Summary

The study aimed to prove EEN is effective for inducing early clinical remission, mucosal healing, promoting fistula closure and reducing the size of abscess to adult CD patients. They plan to include about 50 patients and observe the effect of EEN.

Detailed Description

Not available

Study Timeline

• Study Start: 2013-07
• Primary Completion: 2015-10
• Status Verified: 2016-08
• Study First Submitted: 2016-08-29
• Study First Submitted QC: 2016-09-01
• Last Update Submitted: 2016-09-01
• Study First Posted: 2016-09-02
• Last Update Posted: 2016-09-02

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 48

Inclusion Criteria

• >18 years old
• Patients with CD was diagnosed clinically according to previously established international criteria [9]
• The diagnosis of stricture, fistula and abdominal abscess was confirmed by ultrasound, CT enterography (CTE), and endoscopy. The bowel stricture should mainly cause by inflammation but not fibrosis.

Exclusion Criteria

• Patients do not macth the inclusion criteria and those who refuse to taking part in the study

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Clinical remission after 12 weeks EEN	July 2013 to October 2015

Trial Locations

Locations (1)

The six affiliated hospital of Sun Yat-sen University; 🇨🇳 Guangzhou, Guangdong, China