PROstate MRI Imaging Study (PROMIS): evaluation of multi-parametric magnetic imaging in the diagnosis and characterisation of prostate cancer

niversity College London (UK)0 个研究点目标入组 714 人开始时间: 2011年12月9日最近更新: 2022年4月4日

适应症

试验速览

•1. Are aged 18 years or over, are at risk of prostate cancer and have been advised to have a prostate biopsy
•2. Have a serum prostate-specific antigen (PSA) value of less than or equal 15ng/ml in the last 3 months
•3. Have suspected less than or equal T2 on rectal examination
•4. Are fit for general/spinal anaesthesia and all study procedures

•Current exclusion criteria as of 22/05/2012:
•1. Have been treated using 5-alpha reductase inhibitors at time of registration or during the prior 6 months
•2. Have a previous history of prostate biopsy, prostate surgery or treatment for prostate cancer
•3. Have urinary tract infection or history of acute prostatitis within the last 3 months
•4. Have a contraindication to MRI or any other medical condition precluding study procedures
•5. Previous history of hip replacement surgery, metallic hip replacement or extensive pelvic orthopaedic metal work.
•Previous exclusion criteria:
•1. Have been treated using 5-alpha reductase inhibitors at time of registration or during the prior 6 months
•2. Have a previous history of prostate biopsy, prostate surgery or treatment for prostate cancer
•3. Have urinary tract infection or history of acute prostatitis within the last 3 months
•4. Have a contraindication to MRI or any other medical condition precluding study procedures
•5. Have previous history of hip replacement surgery

发起方

niversity College London (UK)