TRial of OutPatient HYsteroscopy in in-vitro fertilisation (IVF)

Completed

• Conditions: Recurrent in-vitro fertilisation (IVF) failure; Pregnancy and Childbirth; In-vitro fertilisation

• Registration Number: ISRCTN35859078
• Lead Sponsor: Guy's and St Thomas' NHS Foundation Trust (UK)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2009-02-06
• Last Update Posted: 17 October 2016

Recruitment & Eligibility

• Status: Completed
• Sex: Female
• Target Recruitment: 756

Inclusion Criteria

1. Women undergoing an IVF (with or without intracytoplasmic sperm injection) treatment cycle who have had between 2 - 4 failed previous fresh IVF attempts ending in an embryo transfer
2. Aged 36 years or less
3. Willing and able to give informed consent

Women who have had a previous hysteroscopy will be included.

Exclusion Criteria

1. Women who had less than 2 or more than 4 failed fresh IVF attempts ending in an embryo transfer
2. Women aged more than 36 years (i.e. women aged 37 years or more)
3. Presence of submucous or intramural uterine fibroids distorting the uterine cavity or untreated tubal hydrosalpinges

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
ive birth event per cycle started, measured after 9 months of embryo transfer.

Secondary Outcome Measures

Name	Time	Method
1. Embryo implantation rate<br>2. Pregnancy rate per IVF cycle started<br>3. Clinical pregnancy rate per IVF cycle started<br>4. Miscarriage rate per pregnancy achieved<br>Measured 2 and 4 weeks after embryo transfer.