Analysis of Postural Control of COPD Patients (ATTRACTION)
- Conditions
- Chronic Obstructive Pulmonary Disease
- Interventions
- Other: quantified analysis of postural control during activities of daily living
- Registration Number
- NCT05211674
- Lead Sponsor
- University of Rennes 2
- Brief Summary
Chronic Obstructive Pulmonary Disease (COPD) is a common chronic respiratory disease, causing disabling respiratory symptoms and impairing patients' quality of life. Currently one of the leading causes of death worldwide, COPD is a major socio-economic concern. It is also accompanied by extremely frequent extra-respiratory manifestations (or co-morbidities). Among these secondary manifestations, the equilibrium of these patients is subject to modifications: thus, numerous studies have shown that the equilibrium of COPD patients was altered compared to healthy age-matched subjects. This alteration is associated with a greater functional limitation and a higher risk of falling. Although this impairment has been demonstrated clinically, the balance of these patients has never been analysed using quantified movement analysis tools during tasks similar to those performed in daily life. Moreover, the underlying mechanisms remain unknown and the possible associations with several clinical factors of interest (pain, dyspnea, muscle function...) have not yet been assessed. The hypotheses of this project are that (1) the postural control of COPD patients is altered compared to healthy subjects during tasks of daily living and these changes can be characterised. (2) Several clinical factors are associated with these changes.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 32
- COPD patients GOLD stage 2 and 3 (A-D)
- In accordance with Article L1121-8-1 of the Public Health Code, participants must be affiliated to a social security scheme or benefit from such a scheme.
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the presence of long-term or exercise-based oxygen therapy,
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the presence of a medically diagnosed pathology causing manifest disorders of balance,
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the inability to walk 150 m without stopping and to climb or descend stairs,
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a history of pneumonectomy or lobectomy within the last six months,
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the existence of an acute respiratory exacerbation within the last two months,
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the presence of obvious cognitive impairment that impairs comprehension of instructions,
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body mass index less than 21 or more than 35 kg/m².
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Person referred to in articles L. 1121-5 to L. 1121-8 and L. 1121-12 of the public health code:
- Pregnant woman, woman in labour or nursing mother
- Person deprived of liberty by judicial or administrative decision
- Person hospitalised without consent and not subject to a legal protection measure, and person admitted to a health or social establishment for purposes other than research
- Minor
- Person subject to a period of exclusion for other research
- Person of full age subject to a legal protection measure (guardianship, curatorship or safeguard of justice), person of full age unable to express their consent and not subject to a protection measure
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Person under psychiatric care
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description COPD patients quantified analysis of postural control during activities of daily living - Healthy controls quantified analysis of postural control during activities of daily living -
- Primary Outcome Measures
Name Time Method Margins of stability variability Clinical assessment at baseline Coefficient of variation of a postural control parameter related to the centre of mass (CoM) and the base of support of the participant, assessed during the functional tests
Margins of stability Clinical assessment at baseline Postural control parameter related to the centre of mass (CoM) and the base of support of the participant, assessed during the functional tests
Center of Mass velocity Clinical assessment at baseline Parameter of participant's Centre of Mass (CoM) during the functional tests
Center of mass displacement Clinical assessment at baseline Parameter of participant's Centre of Mass (CoM) during the functional tests
- Secondary Outcome Measures
Name Time Method Centre of pressure (CoP) Area Clinical assessment at baseline Parameter of participant's Centre of Pressure (CoP) during the sit to stand and stand to sit tasks of the Glittre-ADL test
Centre of pressure (CoP) velocity Clinical assessment at baseline Parameter of participant's Centre of Pressure (CoP) during the sit to stand and stand to sit tasks of the Glittre-ADL test
Step length Clinical assessment at baseline spatio-temporal parameter of gait assessed during the walking part of the Glittre-ADL test
Completion time of the timed up and go test Clinical assessment at baseline Time to complete the timed up and go test test
Evolution of articular angulations Clinical assessment at baseline Articular angulations assessed at the ankle, knee, hip, spine and thoracic level during the functional tests
Gait velocity Clinical assessment at baseline spatio-temporal parameter of gait assessed during the walking part of the Glittre-ADL test
Gait phases duration Clinical assessment at baseline spatio-temporal parameter of gait assessed during the walking part of the Glittre-ADL test
Step width Clinical assessment at baseline spatio-temporal parameter of gait assessed during the walking part of the Glittre-ADL test
Centre of pressure (CoP) variability Clinical assessment at baseline Coefficient of variation of participant's Centre of Pressure (CoP) during the sit to stand and stand to sit tasks of the Glittre-ADL test
Gait Cadence Clinical assessment at baseline spatio-temporal parameter of gait assessed during the walking part of the Glittre-ADL test
Completion time of the Modified Glittre ADL Clinical assessment at baseline Time to complete the modified Glittre-ADL test