IMRT Lower Limb Soft Tissue Sarcoma
Phase 2
Completed
- Conditions
- Sarcoma
- Interventions
- Radiation: Intensity Modulated Radiation Therapy
- Registration Number
- NCT00188175
- Lead Sponsor
- University Health Network, Toronto
- Brief Summary
Intensity-modulated radiation therapy may make wound healing problems less likely by 1)precisely shaping the region of high radiation dose to the shape of the tissue which harbours tumour cells, and 2) precisely shaping the regions of low radiation dose to the shapes of the normal tissues which are more sensitive to radiation effects.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 59
Inclusion Criteria
- Histologically proven soft tissue sarcoma
- Lesion lies between the iliac crest (hipbone) and the ankle
- Lesion is newly diagnosed
- Assessed by radiation oncologist and surgical oncologist
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Exclusion Criteria
- Benign histologies
- Histologies generally treated with chemotherapy
- Prior or recurrent cancer, except nonmelanomatous skin cancer or carcinoma in-situ of the cervix
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Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Arm && Interventions
Group Intervention Description IMRT for lower limb soft tissue sarcoma Intensity Modulated Radiation Therapy -
- Primary Outcome Measures
Name Time Method Major wound complications within 120 days following surgery 120 days post-op
- Secondary Outcome Measures
Name Time Method Assess acute and late radiation toxicity including limb edema up to120 days
Trial Locations
- Locations (1)
Princess Margaret Hospital
🇨🇦Toronto, Ontario, Canada