Assessment of treatment outcome of Hypofractionated Radiotherapy using modern age radiotherapy technique with concurrent chemotherapy in Locally advanced cancers of Larynx and Hypopharynx
- Conditions
- Health Condition 1: C329- Malignant neoplasm of larynx, unspecified
- Registration Number
- CTRI/2021/04/032672
- Lead Sponsor
- Chittaranjan National Cancer Institute
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Closed to Recruitment of Participants
- Sex
- Not specified
- Target Recruitment
- 0
Locally advanced, non-metastatic histopathology or cytology-proven, squamous cell carcinoma of Hypopharynx and Larynx (T3/T4a N0/N1/N2 M0) sent from multidisciplinary tumour board for CCRT.
Age 20 years to 65 years.
Eastern Cooperative Oncology Group (ECOG) performance status up to 2.
Haemoglobin �10 gm%, white blood cell count �4000/mm3, platelet count �1 lakh/mm3 (initially or after correction by blood transfusion).
Liver function test and kidney function test, both within normal limit.
Baseline audiometry limited to mild sensory neural deficits.
Disease previously treated by radiotherapy, chemotherapy or surgery (other than biopsy and tracheostomy).
Age <20 years or >65 years.
Patients having significant medical co-morbidities.
Pregnancy or lactation.
Evidence of distant metastasis.
Patients unwilling to participate in the study or who do not give consent.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method