which is more effective labour pain reliever paracetamol or tramadol

Phase 1

Completed

• Conditions: Healthy primigravida mothers of age 18 to 35 years without any comorbidities

• Registration Number: CTRI/2018/06/014589
• Lead Sponsor: government

Brief Summary

The objective of the study is to compare intravenous paracetamol and intramuscular tramadol as a intrapartum analgesic in terms of reduction of pain according to visual analogue scale ,duration of labour and mode of delivery, maternal side effects intrapartum and postpartum period, fetal APGAR score at 1 min and 5 min number of cases admitted in NICU, fetal hyperbilirubinimia, and any other specific neonatal adverse effects. We expect our study to prove intravenous paracetamol is more effective intrapartum labour analgesic with fewer maternal and fetal side effects as compared to intramuscular tramadol.

Detailed Description

Not available

Study Timeline

• Study Start: 2018-01-02
• Last Update Posted: 2025-04-30

Recruitment & Eligibility

• Status: Completed
• Sex: Female
• Target Recruitment: 200

Inclusion Criteria

• 1. Primigravidae in spontaneous labour 2. Active phase of labour (cervical dilation of ≥4cm,in the presence of adequate uterine 3 contractions per 10 minutes and each lasting at least for 40 seconds) 3. Maternal age between 18 to 35 years 4. Singleton term pregnancy(37.
• 42 weeks of gestation) 5. vertex- presenting fetus.

Exclusion Criteria

• clinical evidence of cephalopelvic disproportion 2.
• Malpresentation 3.
• scrred uterus , previous cesarean section, hysterotomy or myomectomy 4.medical disorders associated with pregnancy, especially severe anemia, jaundice, hypertension,diabetes, renal impairment 5.
• Fetal distress 6.
• Receiving any regional or parenteral analgesia before recuitment in the study.
• Known hypersensitoivity to the drug family 8.
• induced labour.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Subjective assessment of intrapartum labour pain accordance to visual analouge scale	one year

Secondary Outcome Measures

Name	Time	Method
1. duration of labour	2. mode of delivery

Trial Locations

Locations (1)

NRS Medical college and Hospital; 🇮🇳 Kolkata, WEST BENGAL, India

NRS Medical college and Hospital

🇮🇳Kolkata, WEST BENGAL, India

Rana Mondal

Principal investigator

8777630801

mondalrana099@gmail.com